RAD4 MAINLY FUNCTIONS IN CHK1-MEDIATED DNA DAMAGE CHECKPOINT PATHWAY AS A SCAFFOLD PROTEIN IN THE FISSION YEAST SCHIZOSACCHAROMYCES POMBE.

Rad4 mainly functions in Chk1-mediated DNA damage checkpoint pathway as a scaffold protein in the fission yeast Schizosaccharomyces pombe.

Rad4/Cut5 is a scaffold protein in the Chk1-mediated DNA damage checkpoint in S.pombe.However, whether it contains a robust ATR-activation domain (AAD) required for checkpoint signaling like its orthologs TopBP1 in humans and Dpb11 in budding yeast has been incompletely clear.To identify the putative AAD in Rad4, we carried Beauty Tools out an exte

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La valutazione della produzione sociologica

The paper is a contribution to the debate on the evaluation of the scientific production in the Italian sociology.Starting from an analytical section devoted to the problematic application of the concept of paradigm in sociology as a scientific discipline, the author discusses some negative consequences of its constant pre-paradigmatic status, toge

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